Progress in ATP-competitive Kinesin Spindle Protein Inhibitors as Anticancer Agents / 中国药师
China Pharmacist
;
(12): 420-423,426, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-671083
ABSTRACT
Kinesin spindle protein ( KSP) inhibitors is an important direction for the discovery of anticancer agents. Several KSP in-hibitors have been studied in clinic trials. The discovery of ATP-competitive KSP inhibitors may be a new approach for searching novel a-gents to overcome the mutation-mediated resistance to the allosteric inhibitors. The progress in the discovery of ATP-competitive KSP in-hibitors was reviewed in the paper to provide reference for the further development of KSP inhibitors.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2015
Type:
Article
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