Combined Chemotherapy of HCPT,MTX,Leucovorin and 5-Fu for Metastatic Breast Cancer / 中国肿瘤临床
Chinese Journal of Clinical Oncology
;
(24): 821-823, 2000.
Article
in Chinese
| WPRIM
| ID: wpr-671529
ABSTRACT
Objective:
The therapeutic efficacy and side effects of combined chemotherapy of HCPT,MTX,LV and 5-Fu for metastatic or recurrent breast cancer were evaluated in our study.Methods:
A total of 43 cases of advanced metastatic or recurrent breast cancer were treated with chemotherapy regimen consisting of HCPT 10mg/m2 iv gtt for dl~5,MTX 100mg iv dl,Leucovorin 150mg/m2 iv gtt for d2~4,5-Fu 500mg/m2 iv gtt for dl~5.The cycle was repeated every 4 weeks,and 2 cycles were given as one course.Results:
The overall CR+PR was 47%.One year survival rate was 54% and the median survival interval was 19 months.The main side effects were bone marrow suppression and gastrointestinal reaction.Conclusion:
The combined chemotherapy regimen consisting of HCPT etc is beneficial for metastatic breast cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Clinical Oncology
Year:
2000
Type:
Article
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