Expression of Epidermal Growth Factor, Transforming Growth Factor-αand Epidermal Growth Factor Receptor in Human Pituitary Tumors / 中国肿瘤临床
Chinese Journal of Clinical Oncology
;
(24): 805-807, 2000.
Article
in Chinese
| WPRIM
| ID: wpr-671531
ABSTRACT
Objective:
To explore the mechanism of growth factor autocrine stimulation in human pituitary tumors.Method:
Immunohistochemical analyses of EGF、TGF-αand EGFR were studied on paraffin-embeded sections of 30 pituitary tumors.Results:
Expression of EGFR and its ligand EGF、TGF-αhas a variable stained cells intensity,density and type. EGFR and the ligands expressed in majority of pituitary tumors.Conclusion:
The EGF autocrine stimulation exists in pituitary tumors,and tyrosine kinases inhibitors may be useful for pituitary tumors treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Clinical Oncology
Year:
2000
Type:
Article
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