A clinical study of Chuanhu anti-gout mixture in the treatment of acute gouty arthritis / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
;
(12): 49-51, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-671726
ABSTRACT
In this double-blind,double-dummy,non-inferiority study,144 cases of newly diagnosed acute gouty arthritis were reassigned to Chuanhu anti-gout mixture group (CH,n =72) and colchicine group (Col,n =72).After treatment for 10 days,the total efficiency rates of CH and Col groups were 93.02% and 95.35%,respectively,showing no difference between two groups.Three months later,the overall recurrence rates in CH and Col groups were 12.50% and 13.89% respectively (P<0.05).The incidence of adverse reactions in colchicine group was significantly higher than CH group (34.72% vs 2.78%,P < 0.01).Blood uric acid,alanine aminotransferase,aspartate aminotransferase,and creatinine in CH group were decreased significantly compared with Col group (P<0.05 or P<0.01).The results suggest that the clinical efficacy of Chuanhu anti-gout mixture in the treatment of acute gouty arthritis was not inferior to colchicine,but with higher safety.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Controlled clinical trial
Language:
Chinese
Journal:
Chinese Journal of Endocrinology and Metabolism
Year:
2014
Type:
Article
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