Analysis the significance of cardiac enzymes and troponin in chronic kidney failure combined with acute left heart failure patients / 中国医师进修杂志

ABSTRACT

Objective To analyze the significance of cardiac enzymes and troponin in chronic kidney failure combined with acute left heart failure patients.Methods Thirty-eight chronic kidney failure combined with acute left heart failure patients were chosen as the experimental group,and 42 chronic kidney failure without acute left heart failure patients were chosen as the control group.The changes of creatine phosphokinase isoenzyme-MB (CK-MB),aspartic transaminase (AST),cardiac troponin Ⅰ (cTnI),creatinine were tested and compared.The prognosis of two groups was recorded.Results The level of CK-MB,cTnI in experimental group were significantly higher than those in control group [(36.23 ± 14.27) U/L vs.(14.71 ±8.27) U/L,(11.26 ± 5.04) μ g/L vs.(5.24 ± 2.31) μ g/L] (P ＜ 0.05).The level of AST,creatinine in two groups were higher than normal value,but there were no significant differences between two groups (P ＞0.05).The fatality rate in experimental group was significantly higher than that in control group [47.37％(18/38)vs.16.67％(7/42)](P＜ 0.01).Multiple stepwise regression analysis showed that CK-MB,cTnI were independent factors of prognosis (r =5.03,3.27,P ＜ 0.05).Conclusion The level of cardiac enzymes and troponin are important for the prognosis of chronic kidney failure combined with acute left heart failure patients.