Your browser doesn't support javascript.
loading
Preliminary Study on Effectiveness of Dexamethasone-Soaked Gelatin Sponges for Reducing Pain after Lumbar Microdiscectomy: A Randomized Controlled Trial
Journal of Korean Neurosurgical Society ; : 11-15, 2006.
Article in English | WPRIM | ID: wpr-67206
ABSTRACT

OBJECTIVE:

A prospective, randomized, controlled clinical study is performed to verify the effectiveness of epidural dexamethasone-soaked gelatin sponges to reduce postoperative pain following lumbar microdiscectomy.

METHODS:

Twenty-three patients (10 men and 13 women) undergoing lumbar microdiscectomy were included. Five pieces of gelatin sponge measuring 1 x 1 cm (Gelfoam; Pharmacia & Upjohn, Kalamazoo, MI, USA), soaked with either 5mg dexamethasone or an equal amount (2 mL) of saline, were left on the decompressed nerve root after unilateral hemilaminectomy, flavectomy and discectomy.

RESULTS:

Subjective visual analog scale(VAS) scores of leg pain in the dexamethasone group on the first, third and fifth postoperative days (2.5, 2.5, 1.7, respectively) were significantly lower than in the control group (5.0, 4.8, 3.6) ( P<0.05). No side effects related to the dexamethasone-soaked gelatin sponges were observed.

CONCLUSION:

The intraoperative application of dexamethasone-soaked gelatin sponges during lumbar microdiscectomy can provide effective postoperative analgesia without complications.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Pain, Postoperative / Porifera / Dexamethasone / Prospective Studies / Diskectomy / Gelatin / Analgesia / Leg Type of study: Controlled clinical trial / Observational study Limits: Humans / Male Language: English Journal: Journal of Korean Neurosurgical Society Year: 2006 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Main subject: Pain, Postoperative / Porifera / Dexamethasone / Prospective Studies / Diskectomy / Gelatin / Analgesia / Leg Type of study: Controlled clinical trial / Observational study Limits: Humans / Male Language: English Journal: Journal of Korean Neurosurgical Society Year: 2006 Type: Article