Establish the reference value about index of serum thyroid specific during pregnancy women / 国际检验医学杂志

ABSTRACT

Objective To establish the reference value about index of serum thyroid specific during pregnancy ,Improve the birth population quality in this district .Methods Collect the blood serum sample of normal pregnant women according to Diagnosis and treatment of thyroid disease during pregnancy and postpartum Guide,to establish the reference value about index of serum thyroid specific during pregnancy .Total 167 cases were collect ,the first trimester were 47 cases ,the second trimester were 86 cases ,and the third trimester were 34 cases .The TSH and FT4 were detected in the cobas e 601 .The mean and standard deviation of TSH and FT4 in the three period of pregnancy were performed with SPSS14 .0 then established the the 95% confidence interval of TSH and FT4 of the three period of pregnancy .That was the the reference value about index of serum thyroid specific during pregnancy .Re‐sults The reference value of the TSH was 0 .05-2 .90 mIU/L in the first trimester ,FT4 was 12 .5-18 .3 pmol/L in the first tri‐mester ;The reference value of TSH was 0 .2-3 .63 mIU/L in the second trimester ,FT4 was 9 .99-16 .2 pmol/L in the second tri‐mester ;The reference value of TSH was 0 .17-4 .90 mIU/L in the third trimester ,FT4 was 9 .34-13 .9 pmol/L in the third tri‐mester .Conclusion Electrochemiluminescence detect the reference value about index of serum thyroid specific during pregnancy on Cobas e 601 ,could improve the detection rate of local gestational thyroid dysfunction ,and lay a solid foundation for the prenatal and postnatal care and improve the quality of the population .