MRI for differentiating high-grade from low-grade of limb long bone chondrosarcoma / 重庆医学

ABSTRACT

Objective To investigate the imaging differentiation between high-grade and low-grade limb of long bone chon-drosarcoma.Methods The MRI imaging features in 23 cases of pathologically proven limb long bone chondrosarcomas were retro-spectively analyzed,including 13 cases of low-grade and 10 cases of high-grade.The MRI imaging features including endosteal scal-loping lesion,cortical thickening,cortical destruction,bone expansion,soft tissue mass,bone marrow edema,soft tissue edema,calci-fication,hemorrhage,tumour maximal radial line and enhancing features were performed the statistical analysis.Results 13 cases were the low-grade chondrosarcomas,including atypical cartilaginous tumour and grade 1 chondrosarcomas,10 cases were high-grade chondrosarcomas (8 cases of grade Ⅱ chondrosarcomas,1 case of gradeⅢ chondrosarcomas and 1 case of dedifferentiated chondrosarcomas).Cortical destruction,soft tissue mass and soft tissue oedema had statistical differences between the low-grade and high-grade.Bone marrow had statistically significant difference.Calcification +(SC<1/3ST)had statistical difference between the low-grade and the high-grade.Calcification ++(1/3 STchondrosarcomas was (6.2 ±2.9)cm and which in the high-grade was (9.3±5.2)cm,showing statisti-cal difference between them.The speckling and sieving enhancement had statistical differences between the low-grade and high-grade chondrosarcomas.Conclusion In the MRI imaging features of chondrosarcoma,cortical destruction,soft tissue mass,bone marrow edema,soft tissue edema,bone marrow edema,calcification proportion,tumor maximal radial line and enhancing features can be valuable to differentiate low-grade from high-grade limb long bone chondrosarcoma.