Alterations in antioxidants enzymes and Malondialdehyde status in preeclampsia
Asian Pacific Journal of Tropical Biomedicine
;
(12): 750-752, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-672463
ABSTRACT
Objective:
This study was done to determine and evaluate the level of antioxidant enzymes and malondialdehyde (MDA) in preeclamptic women.Method:
100 preeclamptic and 100 healthy pregnant women between the age of 20-32 attending General Hospital Owerri were selected in this study. Fasting veinous blood was collected and was used for the estimation of antioxidant enzymes and malondiadehyde.Result:
The result obtained showed that the level of MDA was significantly increased in preeclamptic pregnant women when compared with the healthy control (P<0.05). On the other hand, the level of catalase, superoxide dismutase and glutathione peroxidase (GPX) was significantly reduced in preeclamptic women when compared with the control(P<0.05).Conclusions:
This observation showed that the antioxidants are excessively used to attenuate the cellular changes mediated by free radicals. Hence, the level of antioxidants are depleted.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Asian Pacific Journal of Tropical Biomedicine
Year:
2012
Type:
Article
Similar
MEDLINE
...
LILACS
LIS