Serum Levels of Soluble Intercellular Adhesion Molecule-1(sICAM-1) in Women with Pregnancy-induced Hypertension (PIH) and Its Roles in the Pathogenesis of PIH / 中华围产医学杂志

ABSTRACT

Objective To study the roles of soluble intercellular adhesion molecule 1(sICAM 1) in the pathogenesis of pregnancy induced hypertension (PIH). Methods Serum levels of sICAM 1 were measured by enzyme linked immunosorbent assay(ELISA) in 65 women with PIH (PIH group : 15 mild PIH, 24 moderate PIH and 26 severe PIH) and 25 normal pregnant women (control group). The serum levels of IL 1? and TNF ? were measured by chemiluminescent ELISA at the same time. Results Serum concentrations of sICAM 1 were significantly higher ( P