A study on the relationship between anatomic site distribution and clinical pathology of colorectal cancer / 中国普通外科杂志

ABSTRACT

Objective To study the relationship between anatomic site distribution and clinical pathologic characteristics of colorectal cancer(CRC). Methods Clinical data were collected from 790 patients in Nanfang Hospital admitted from 1990 to 1999. Results Mucous adenocarcinoma accounted for 26 5% in proximal colon, 10 1% in distal colon and 9 4% in rectum; Poor differentiation cancer accounted for 14 5%,5 7% and 10 0% respectively, and 85 3%,75 3% and 77 1% was in advanced stage of cancer (Dukes B, C and D) in proximal, distal colon and rectum respectively. There was significant difference( P 0 05) in pathologic type and tumor′s stage. Conclusions Proximal colon cancer has some significantly different characteristics from distal colon or rectal cancer, with more mucous adenocarcinoma, poor differentiation and later tumor stage.