Study on the Formula Selection of Total Alkaloid Tablets of Peganum Harmala by Orthogonal Design / 中国药房

ABSTRACT

OBJECTIVE:To optimize the best formula of the total alkaloid tablets of peganum harmala.METHODS:3 levels from each of the amount of four factors-excipient calcium carbonate,tween-80,starch and emollient(magnesium stearatefrench chalk) were subjected to the orthogonal design with the parameter of dissolution(Td) of the harmine in tablet as an index.RESULTS:The amount of tween-80 and calcium carbonate(P