Distribution of Human CYP3A Activity in 544 Children at School Age in Shanghai / 中国药房
China Pharmacy
;
(12)2005.
Article
in Chinese
| WPRIM
| ID: wpr-674121
ABSTRACT
OBJECTIVE:
To establish a scientific evidence for evaluation of individualized administration among children.METHODS:
Hydrocortisone probe was used for determination of CYP3A activity in children with quantitative method.RESULTS:
CYP3A activity in the health children volunteers showed Gaussian distribution in the form of natural logarithm,the average value was1.69?1.04,with the value of1.63?0.99in males and1.75?1.09in females.CONCLUSION:
There is no significant difference in CYP3A activity between the two sexes.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2005
Type:
Article
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