ULTRASTRUCTURAL STUDY ON EFFECTS OF PIG BILE EXTRACTS AND SODIUM DEOXYCHOLATE ON HUMAN TRICHOMONAS VAGINALIS IN VITRO / 西安交通大学学报(医学版)

ABSTRACT

In ultrastructural level, this paper shows that the pig bile extracts and its effective constituent, the sodium deoxycholate, could fragment the Trichomonas vaginalis in vitro, The flagellum and caudal projection were splitted up; the plasma membrane, the intracellular membrane system, such as the limiting membranes of hydrogcnosome, phagosome and nuclear envelope were injured too; and cytoplasm was condensed, even the whole body was fragmented. The mechanism of the effeces is probably due to the fact that the surface activity of the drugs accelerated degradation of lipids which are made of the biomembrane system of human trichomonas vaginalis.