THE STUDY OF T LYMPHOCYTE SUBSETS AND SUPPRESSOR CELL ACTIVITY IN CHILDREN WITH PRIMARY NEPHRITIC SYNDROME / 西安交通大学学报(医学版)

ABSTRACT

The peripheral blood T lymphocyte subsets and ConA-induced suppressor cell activity (ConA-SCA) were determined in 37 patients with primary nephritic syndrome(PNS). The results showed that the patients in initial onset had the abnormal number and function of T lymphocytes, which returned to a normal level with treatment with steroid and improvement of patients'condition. The indings suggest that the immunoregulatory imbalance of this disease may be a primary change and play an important role in pathogenesis of PNS.