Human ?-cells destruction correlates with Fas expression on ?-cells induced by IFN-? and TNF-? / 中国免疫学杂志
Chinese Journal of Immunology
;
(12)1999.
Article
in Chinese
| WPRIM
| ID: wpr-674724
ABSTRACT
Objective:
To study the effect of increased expression of Fas on the killing of ? cellsMethods:
The level of Fas expression and apoptosis of human ? cells strain (NIT) were detected by FACSResults:
There is no Fas expression on NIT But Fas expression can detected by culturing NIT with IFN ? and/or TNF ? The apoptosis of NIT induced by sFasL and anti Fas correlates with the level of Fas expressionConclusion:
Fas expression induced by cytokine may represent a factor for the initiation of ? cells destruction
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Immunology
Year:
1999
Type:
Article
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