Oxidation Damage of Sulfur Dioxide Inhalation on Erythrocytes of Rats / 环境与健康杂志
Journal of Environment and Health
;
(12)1992.
Article
in Chinese
| WPRIM
| ID: wpr-674890
ABSTRACT
Objective The aims of the present study are to further investigate mechanism of toxicological role of sulfur dioxide (SO 2) exposure on mammalian animals Methods Effects of SO 2 inhalation (14 mg/m 3) on activities of antioxidative enzymes and levels of lipid peroxidation in erythrocytes of male rats were determined Results SO 2 inhalation caused the decrease of Cu,Zn SOD activity,the increase of GSH Px activity,and no change of CAT activity,and the increase of level of lipid peroxidation in rat erythrocytes Conclusion Primary mechanism of toxicological role of SO 2 exposure at low concentrations may be that oxidation damages of lipid and other biological large moleculars are caused by SO 2 producing reactive oxygen species
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Environment and Health
Year:
1992
Type:
Article
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