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Effect of cyclophosphamide pulse therapy on levels of serum interleukin-6 in patients with lupus nephritis / 中国免疫学杂志
Chinese Journal of Immunology ; (12)2000.
Article in Chinese | WPRIM | ID: wpr-674942
ABSTRACT

Objective:

To investigate role of interleukin 6(IL 6) in the pathogenesis of lupus nephritis(LN) and effect of cyclophosphamide pulse therapy on production of IL 6.

Methods:

Serum IL 6 levels of pre and post therapy were determined by using sandwich ELISA in LN patients.

Results:

In the active LN patients,serum levels of IL 6 were significantly higher than those in inactive LN patients and healthy controls(268.26?79 64 ng/L vs 62.40?45 23 ng/L,268 26?79 64 ng/L vs 50.36?42 75 ng/L,P16 g/L were significantly higher than those in other active LN patients (329.58?94.21 ng/L vs 233.22?43.56 ng/L,P

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Immunology Year: 2000 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Immunology Year: 2000 Type: Article