EXPRESSION OF p16 AND p27 IN HUMAN GIANT CELL TUMORS OF BONE AND OSTEOSARCOMAS / 肿瘤研究与临床

ABSTRACT

0.05) while those between GCT Ⅰ and the collection of GCT Ⅱ and GCT Ⅲ were significant ( P 0.05).Conclusion:The results indicated that neither the p16 positive rate nor the p27 positive rate could be used independently for defining grade of malignancy and estimating prognosis of malignant bone tumors though p16 and p27 might play important roles in the genesis of bone tumors.