Expression of uPA,uPAR,PAI-1 in three nasopharyngeal carcinoma cell(NPC) lines with different ability to metastasize / 中国癌症杂志
China Oncology
;
(12)1998.
Article
in Chinese
| WPRIM
| ID: wpr-675082
ABSTRACT
Purpose:
To study the expression of uPA, uPAR ,PAI 1 in 3 nasopharyngeal carcinoma cell lines CEN 2Z,CEN 2Z H5,CEN 2Z H5 9,with different ability to metastasize through lymph.Methods:
RT PCR was used to detect expression of uPA,uPAR,PAI 1 at levels of mRNA.Results:
mRNA expression of uPA,uPAR was the highest in CNE 2Z H5 9,whereas the lowest in CNE 2Z;mRNA expression of PAI 1was detected in CNE 2Z and CNE 2Z H5, but revealed no differences,but not in CNE 2Z H5 9.Conclusions:
uPA?uPAR may promote the metastasis and invasion of NPC,whereas PAI 1 maybe inhibit it
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Oncology
Year:
1998
Type:
Article
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