Non-operative treatment of patients with stageⅠandⅡnon-small-cell lung cancer / 中国癌症杂志

ABSTRACT

Purpose:To evaluate the efficacy of radiotherapy and chemotherapy in patients with stage Ⅰ and Ⅱ non small cell lung cancer.Methods:From 1991 to 1996,21 patients with stage Ⅰ and Ⅱ non small cell lung cancer were treated.According to the 1997 UICC Staging System, 3 patients had stage Ⅰb disease, 2 stage Ⅱa,and 16 stage Ⅱb.16 patients were confirmed by histopthology,and 5 cases by cytopathology.18 patients had squamous cell carcinoma,2 adenocarcinoma,and 1 mixed squamous cell and adenocarcinoma.21 patients were treated by 6 Mv X or 18 Mv X, received 56 Gy～70 Gy (total dose), at 2 Gy per day.Chemotherapy 19 patients were treated by MVP(MMC?VDS?DDP). 2 squamous patients were not treated with chemotherapy.19 patients were treated with chemotherapy after radiotherapy 1～7 weeks,and were treated 1～5 cycles.Results:The overall 5 year survial for all patients was 19%.19 patients have died,13 died of tumor,and because of local failure and metastasis.6 patients died of other causes.Conclusions:Non operative treatment is an effective treatment for non small cell lung cancer.