Studies on mass survery of 413164 persons for NPC / 中国癌症杂志

ABSTRACT

Purpose:To analyze the correlation of positive VCA IgA and EA IgA antibodies, sex and age to diagnosis of NPC through a survey of 413 164 persons. Methods:To diagnose NPC by detecting VCA IgA and EA IgA antibodies with ELISA, indirect nasopharynxscopes and histopathologic examination. Results:In 413 164 persons, 12 629 cases with positive VCA IgA antibody were found. The positive rate was 3.06%. The results indicated that the rate of positive antibody was not related to sex, but was associated with age. In those cases, 174 were diagnosed as NPC, and 151 were in early stage of NPC. The early diagnosis rate was 86.78%, and over all NPC diagnosis rate was 42.11/100000 in the survey. The diagnosis rate was also related with age. Conclusions:Methods of survey can be beneficial for early prevention and early diagnosis of NPC, especially for those aged over 35 year.