A self-made liposome perfluorocarbon contrast agent enhancing the grey scale of normal rabbit kidney:experimental study / 中华超声影像学杂志

ABSTRACT

Objective To investigate the effect of a self made liposome perfluocarbon ultrasound contrast agent in enhancing grey scale imaging of normal kidney.Methods The kidneys of 10 normal rabbits were imaged with second harmonic imaging before and after intravenous injection of the liposome contrast agent at a dose of 0.01 ml/kg. The subjective scores and video intensities were used to evaluate contrast effects. Results The renal cortex,medulla and sinus grey scale imaging were greatly enhanced after injection, and the notable enhancement time of renal cortex,medulla and sinus could last for 52 min,2 min 20 s,1 min 40 s,respectively. Conclusions The self made liposome perfluocarbon contrast agent can significantly long time enhance the grey scale of the kidney.