Experimental study on anti-tumor effect with Shenqi compound recipe / 中国免疫学杂志

ABSTRACT

Objective:To study the inhibitive effect of SQ on HcaF 16 A 3 cells in vivo.Methods:SQ was given to BALB/C mice after bearng tumors for 10 consecutive days.The therapeutic effect was determined by measurement to tumor weight?immunological function and morphological changes.Flowcytometry and electronic microscope were used to evaluate the distribution of cell cycle.Results:The inhibition rate was 65.68%,NK/M? activities and cytokine production were enhanced by SQ,cell cycle was stopped at the S phase.Necrosis could be seen nuder microscope and characteristic apoptotic body could be seen under electronic microscope.Conclusion:SQ had a significant anti tumor effect by regulate immune system and inhibit tumor cell proliferation.