Expression of NF-?B, c-myc and ICAM-1 in colorectal cancer and its relation to the indices in clinical pathology / 中国癌症杂志

ABSTRACT

Purpose:To investigate the expression of nuclear factor kappa binding (NF ?Bp65),c myc and intercellular adhesion molecule 1(ICAM 1) in colorectal cancer and its relation to clinicopathology.Methods:50 colorectal cancer patients who underwent radical surgery were studied, the expression of NF ?Bp65, c myc and ICAM 1 in them were examined by immunohistochemical method.Results:①In normal colon there was weak expression of NF ?Bp65, no expression of c myc and ICAM 1, NF kBp65,C myc and ICAM 1 were strongly expressed in colorectal cancer than in normal colon( P