Study on the inhibition of allogeneic transplantation rejection by the B7 antisense peptide / 中国免疫学杂志

ABSTRACT

95%,WT= 1 271 6 .Lymphoproliferation reaction of the splenocytes derived from BALB/C mice was inhibited by stimulating with the antisense peptide pre treatment of allogeneic splenic cells and cardiac cells of C57 mice.The inhibition rates up to 38 4% and 36 6%.Pre treatment of allogeneic cardiac grafts resulted in prolonging the survival of cardiac transplantation 5 4 days more than the control group(n=6,P