Immunohistochemical Study about Expression of Caspase-3 in Hemangiomas / 中国普外基础与临床杂志
Chinese Journal of Bases and Clinics in General Surgery
;
(12)2003.
Article
in Chinese
| WPRIM
| ID: wpr-675602
ABSTRACT
Objective To study the relationship between expression of Caspase 3 and regression of hemangioma. Methods Caspase 3 expression was detected in 79 hemangiomas and 5 normal skin tissues by immunohistochemistry (SP). Results In 79 hemangiomas, the positive rates of Caspase 3 expression in proliferating, involuting and involuted phases were 52.4%, 91.2% and 83.3%, respectively. The expression of Caspase 3 in involuted and involuting phases was higher than proliferating phase( P 0.05). Conclusion Caspase 3 is involved in the converting of hemangiomas from proliferating phase into involuting phase. The activation of Caspase 3 may induce apoptosis of endothelial cells, thus leading to the regression of hemagioma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Bases and Clinics in General Surgery
Year:
2003
Type:
Article
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