Melatonin decreases expression of transforming growth factor-?_1 in renal cortex of diabetic rats / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-676135
ABSTRACT
Transforming growth factor-?_1 (TGF-?_) mRNA or protein expression in renal cortex of diabetic rats was assessed by real-time quantitative RT-PCR with SYBR Green,immunohistochemistry or Western blot.After melatonin treatment,the expressions of TGF-?_1 mRNA and protein were decreased,suggesting that beneficial effect of melatonin may result from its antioxidative property and inhibiting TGF-?_1 expressions.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Endocrinology and Metabolism
Year:
2001
Type:
Article
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