Is height a risk factor for colorectal adenoma?
The Korean Journal of Internal Medicine
;
: 653-659, 2016.
Article
in English
| WPRIM
| ID: wpr-67616
ABSTRACT
BACKGROUND/AIMS:
Although it is generally known that the risk for all types of cancer increases with adult height, combined and for several common site-specific cancers (including colon and rectal), evidence is limited for adenomas, which are precursors to colorectal cancer. We evaluated the association between height and risk of colorectal adenoma at various stages of the adenoma-carcinoma pathway.METHODS:
We conducted a retrospective study using data from patients who had undergone a complete colonoscopy as part of a health examination at the Health Promotion Center of Samsung Medical Center between October 13, 2009 and December 31, 2011. A total of 1,347 male subjects were included in our study. Multivariate logistic regression analysis was used to evaluate the association between height and colorectal adenoma.RESULTS:
Each 5-cm increase in height was associated with 1.6% and 5.3% higher risks of advanced colorectal adenoma and high-risk colorectal adenoma, respectively, but associations were not significant after adjusting for age, body mass index, metabolic syndrome, alcohol intake, smoking, family history of colorectal cancer, and regular aspirin use (p = 0.840 and p = 0.472, respectively).CONCLUSIONS:
No clear association was found between colorectal adenoma risk and height. Unlike other site-specific tumors reported to have a consistent relationship with height, the association between colorectal tumor and height remains controversial.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Smoke
/
Body Height
/
Body Weight
/
Colorectal Neoplasms
/
Smoking
/
Adenoma
/
Body Mass Index
/
Logistic Models
/
Aspirin
/
Retrospective Studies
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
The Korean Journal of Internal Medicine
Year:
2016
Type:
Article
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