Role of NF-?B in hepatocyte apoptosis induced by intestinal perforations due to abdominal firearm wound / 中国现代普通外科进展
Chinese Journal of Current Advances in General Surgery
;
(4)2004.
Article
in Chinese
| WPRIM
| ID: wpr-676688
ABSTRACT
Objective:
To investigate the role of NF-?B in signal transduction of hepatocyte apoptosis in liver injury.Methods:
A total of 42 Chang-Bai piglets were divided into 7 groups control group, 1, 2, 4, 8, 12, and 24 hours wound group. The model of intestinal perforations due to abdominal firearm wound was established in wound groups. Hepatic NF-?B activity was measured with immunohistochemical staining and image analysis in all groups. Hepatocyte apoptosis indexes and serum ALT levels were also determined.Results:
Levels of hepatic NF-?B activity in wounded groups were significantly elevated compared with control group, and there were two peaks (1 and 8 hours group P
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Chinese Journal of Current Advances in General Surgery
Year:
2004
Type:
Article
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