Effect of 1-deoxynojirimycin on high glucose-stimulating proliferation of rat mesangial cells / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
; (12)2000.
Article
in Zh
| WPRIM
| ID: wpr-676724
Responsible library:
WPRO
ABSTRACT
The effect of 1-deoxynojirimycin(DNJ)on the proliferation of rat mesangial cells was observed and its mechanism was explored.The results showed that DNJ significantly inhibited the proliferation of rat mesangial cells induced by high glucose in time-and dose-dependent manners.DNJ significantly decreased expressions of?-smooth muscle action(?-SMA),integrin?1 mRNA and protein and focal adhesion kinase (FAK)protein stimulated by high glucose in rat mesangial cells(P
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Endocrinology and Metabolism
Year:
2000
Type:
Article