Effect of bone marrow cell on chemotaxis of aggregation of macropahges in venous thrombosis / 中国现代普通外科进展
Chinese Journal of Current Advances in General Surgery
;
(4)1999.
Article
in Chinese
| WPRIM
| ID: wpr-676883
ABSTRACT
Objective:
To discuss the effect of bone marrow on chemotaxis of aggregation of macrophages in venous thrombosis.Methods:
SD adult rats were divided randomly into normal group,sham operation group,thrombus group and rhG-CSF group.Peripheral blood was harvested at 30min before operation and on the 7th and 14th day after operation.Level of MCP-3 in peripheral blood was detected with ELISA.Inferior vena cava specimens of thromus group and rhG-CSF group were collected at postoperative 7th and 14th day.With the application of RT-PCR,expression of MCP-3mRNA in thrombus was detected.Results:
The level of MCP-3 in peripheral blood of rhG-CSF group was significantly higher than that before operation and also higher than the levels of MCP-3 in peripheral blood of sham operation group and thrombus group on the 14th day after operation,(P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Current Advances in General Surgery
Year:
1999
Type:
Article
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