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Preliminary immunopathological study in alopecia areata / 第三军医大学学报
Journal of Third Military Medical University ; (24)1984.
Article in Chinese | WPRIM | ID: wpr-676974
ABSTRACT
Studies of the scalps from 42 patients with alopecia areala are given,using direct immunofluorescence ( DIP).Langerhans cells (LC)and T-lyrn hocytc subsets are observed.There is no significant difference between the number of OKT6 cells and Ia+ cells in the epidermis of all groups and the control.LC is seen in hair-bulb in many patients and most frequently in active stage.The main change of LC in hair follicle is increasing of T6+Ia- cells,not significant of T6+Ia+ cells.Most of the infiltrates around the hair follicles are T( OKT3+) cells.T4+cells number and T4/T8 ratio in active arc larger than in resting and recovering stages.DIF shows 88% of the patients having deposits of C3,IgG,and IgM.This suggests that alopecia areata may be the disorder of immnue associated with cellular and humoral immunity.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Journal of Third Military Medical University Year: 1984 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Journal of Third Military Medical University Year: 1984 Type: Article