MECHANISM OF KILLING SCHISTOSOMA JAPONICUM (CHINESE STRAIN)SCHISTOSOMULA IN VITRO. ANTIBODY-DEPENDENT MURINE NEUTROPHIL-MEDIATED CYTOTOXICITY AGAINST SCHISTOSOMULA / 中国血吸虫病防治杂志

ABSTRACT

In this study, antibody-dependent murine neutrophil-mediated cytotoxicity (ADCC)against schistosomula of Schistosoma japonicum (Chinese strain) were demonstrated in vitro by use of immune effector mechanism analysis system. The results showed that neutrophils from the normal mice could mediate the antibody-dependent ADCC reaction against the schistosomula of Schistosoma japonicum, This ADCC reaction was not dependent on the complements, the complements could not enhance the ADCC reaction mediated by the neutrophils.