A clinical study of the effects of highly selective vagotomy and antrum mucosa resection on gastric acid and serum gastrin levels / 第三军医大学学报

ABSTRACT

The association of selective vagotomy and antrectomy for the treatment of duodenal ulcer is considered as the best procedure to prevent ulcer recurrenceut it brings about too many operative sequelae.The authors of this paper used highly selective vagotomy in association with antrum mocosa resection to treat duodenal ulcer and the effects on gastric acid level and serum level of gastrin were compared with those after selective vagotomy and antrectomy.It was found that the reduction of gastric acid and the changes of serum gastrin were similar after the 2 operative procedures.It is believed that the association of highly selective vagotomy and antrum mocosa resection is the better operative treatment for duodenal ulcer than the association of selective vagotomy and antrectomy since the former can both reduce the number of postoperative sequelae and preserve the functions of the pylorus and the antrum.