Relation between alteration in myocardium chymase-like activity and cardiac hypertrophy in pressure-overload hypertrophy rats / 中国药理学通报

ABSTRACT

AIM To investigate the relationship between myocardium chymase like activity and cardiac hypertrophy. METHODS The model of pressure overload hypertrophy was eatablished in rats. The changes of the HW/BW and LVH/BW and myocardium chymase like activity were investigated in the two groups of rats. RESULTS In cardiac hypertrophic rats 2,6,12 weeks after operation,the HW/BW and LVH/BW and myocardium chymase like activity were all significantly increased ( P