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Hyperinsulinemic Hypoglycemia Caused by Acute Reduction of Renal Function on an Eldery Patient Without Diabetes
Journal of the Korean Geriatrics Society ; : 34-39, 2015.
Article in Korean | WPRIM | ID: wpr-67732
ABSTRACT
In patient with renal failure, hypoglycemia may develop because of decreased caloric intake, diminished renal insulin degradation and clearance, reduced renal gluconeogenesis and hepatic glucose production, impaired release of counter-regulatory hormone such as glucagon and epinephrine. We report here on a 80-year-old female patient with hypoglycemia due to endogenous hyperinsulinemia with acute kidney injury. She had chronic kidney disease and had no history of diabetes mellitus or insulin use. She had experienced recurrent hypoglycemia despite of intravenous dextrose injection and eventually generalized tonic clonic seizure occurred as a result of hypoglycemia. As serum creatinine level decreases, serum insulin and C-peptide level decreased and hypoglycemia was not occurred. We present this case along with a review of the literature.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Seizures / C-Peptide / Energy Intake / Glucagon / Epinephrine / Creatinine / Diabetes Mellitus / Renal Insufficiency / Renal Insufficiency, Chronic / Acute Kidney Injury Limits: Aged / Aged80 / Female / Humans Language: Korean Journal: Journal of the Korean Geriatrics Society Year: 2015 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Seizures / C-Peptide / Energy Intake / Glucagon / Epinephrine / Creatinine / Diabetes Mellitus / Renal Insufficiency / Renal Insufficiency, Chronic / Acute Kidney Injury Limits: Aged / Aged80 / Female / Humans Language: Korean Journal: Journal of the Korean Geriatrics Society Year: 2015 Type: Article