Study on left ventricular diastolic function in the patients with coronary artery disease by tissue Doppler imaging and color Doppler echocardiography / 第二军医大学学报

ABSTRACT

Objective: To study left ventricular diastolic function (LVDF) in patients with coronary artery disease(CAD) by tissue Doppler imaging (TDI) and color Doppler echocardiography. Methods: The maximum velocity ( V max ) and time velocity integration(TVI) in early and late diastolic stage of mitral valve orifice of 80 patients with CAD and 79 normal subjects were measured by color Doppler echocardiography at apical 4 chamber view. Meanwhile, the V max and/or TVI of the myocardial motion spectrum of left ventricular lateral wall near the mitral valve annulet were measured by TDI. These data were compared and analysed by statistical method. Results: In the normal subjects, the older the subject, the lower the V max and TVI of early diastolic stage, the higher the V max and TVI of late diastolic stage. In CAD group, changes were not associated with ages and were affected by the degree of the myocardial pathology. The LVDF couldn't be exactly judged by color Doppler echocardiography when pseudonormalization blood flow spectrum appeared, but TDI technique was relatively sensitive. Any regional myocardial motion could be measured by TDI according to the examiner's design. Conclusion: LVDF by color Doppler echocardiography is simple and convenient. TDI technique can be used for determining overall LVDF and left ventricular systolic function. [