EFFECT OF VITAMIN C ON THE ELECTROPHYSIOLOGICAL PROPERTY OF MYOCARDIAL CELLS OF THE RATS FED LOW SELENIUM AND LOW CHROMIUM FODDER / 营养学报
Acta Nutrimenta Sinica
;
(6)1956.
Article
in Chinese
| WPRIM
| ID: wpr-677368
ABSTRACT
Objective:
To elucidate the etiology of the impairment of myocardial cells in Keshan disease.Methods:
With intracellular microelectrode technique, we observed the electrophysiological changes of the eight groups of rats fed separatelynormal, low Se, low Se+high VC, low Cr, low Cr+high VC, low Se+low Cr and low Se+low Cr+high VC fodders.Results:
Compared with the control, there was no change in low Cr group. However, in low Se group, RP and APA decreased, APD 50 and APD 90 prolonged. In low Se+low Cr group, APA decreased, APD 50 and APD 90 prolonged significantly. In low Se with high vitamin C groups, though RP still decreased, no change had been detected on APA and APD.Conclusion:
It is suggested that Se and Cr deficiency may jointly change the electrophysiological properties of myocardial cells significantly. However, vitamin C may protect myocardial cells against the injury effectively.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Acta Nutrimenta Sinica
Year:
1956
Type:
Article
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