Effects of ?-sodium aescinate on hemorrhage brain edema and AVP contents in rats / 第二军医大学学报

ABSTRACT

Objective: To observe the content of AVP changes in brain regions and pituitary of intracerebral hemorrhagic rats before and after treatment by ? sodium aescinate. Methods: Animal model was established by injecting collagenase into left caudoputamen of adult rats. Radioimmunoassay(RIA) was performed to measure the content changes of AVP, dye wet Weight methods was used to measure the changes of water contents in brain. Results: Compared with control group, the water content was increased significantly ( P