Effect of breviscapine on delayed outward potassium current in single ventricular cell of guinea pig / 中国药理学通报
Chinese Pharmacological Bulletin
; (12)1987.
Article
in Zh
| WPRIM
| ID: wpr-677780
Responsible library:
WPRO
ABSTRACT
AIM To Investigate the effect of breviscapine on delayed outward potassium current in single ventricular cell of guinea pig. METHOD Using whole cell patch clamp technique. RESULTS Breviscapine enhanced I k dose dependently. Breviscapine with the concentration of 0^01 and 0^02 mg?L -1 increased I k by 44.6% and 78.3%,respectively. The effect could be reversed by washing. CONCLUSION Breviscapine can open the K + channel and incrase I k .
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WPRIM
Language:
Zh
Journal:
Chinese Pharmacological Bulletin
Year:
1987
Type:
Article