Clinical analyses of 87 cases of cervical intraepithelial neoplasia / 第三军医大学学报

ABSTRACT

Objective To observe the clinical behaviors of cervical intraepithelial neoplasia (CIN) for early diagnosis to improve the therapeutic efficacy Methods Eighty seven cases with different grades of CIN confirmed with colposcopy and pathological examination were reviewed for the clinical features and the results from colposcopy, pathology, testing for HPV (human papillomavirus) All patient were treated with various methods and followed up Results Most patients with CIN were in childbearing period and sought for medical advices because of increased leucorrhagia and/or bloody leucorrhea, postcoital bleeding for a comparatively long course Chronic cervicitis was often found in these patients Contact bleeding and HPV infection were common in patients with CINⅡand CIN Ⅲ Patients with CIN Ⅰ were regular followed up or treated with electrocautery, those with CIN Ⅱ were treated with conization or hysterectomy, and for those with CIN Ⅲ, hysterectomy was performed The outcomes of all patients were satisfactory after treatment Conclusion The most common sign for the patients with CIN is postcoital bleeding For correct diagnosis of CIN, colposcopy and together pathological examimotion is recommended High risk HPV detection is a good prognostic factor After treatment, the patients with different grades of CIN should be followed up regularly