The gene expressions of collagen types Ⅰ and Ⅲ in obstructive low compliant bladder in rats / 第三军医大学学报

ABSTRACT

Objective To detect the gene expressions of collagen types Ⅰ and Ⅲ in obstructive low compliant bladder in rats. Methods The expressions of collagen types Ⅰ and Ⅲ mRNA in rat bladder tissues were detected by in situ hybridization. Results Compared with those in the normal control, the gene expressions of collagen types Ⅰ and Ⅲ in smooth muscle of low compliant bladder were up regulated. Type Ⅲ gene expression was more obvious than type Ⅰ. Conclusion The expressions of collagen types Ⅲ and Ⅰ in obstructive low compliant bladder in rats are up regulated, which is related with low compliant bladder after obstruction.