The role of ATP-ubiquitin-proteasome pathway in the degradation of skeletal muscle protein during cancer cachexia / 肠外与肠内营养

ABSTRACT

The progressive loss of skeletal muscle protein observed in cancer cachexia may have a negative impact on both the quality of life and the survival time of patients. In recent years, accumulating evidences suggest that the ATP ubiquitin proteasome pathway may be crucial in muscle cachexia. The review is mainly about the role of the ATP ubiquitin proteasome pathway in the degration of skeletal muscle protein during cancer cachexia.