Malaria vaccine: current status and perspective / 第二军医大学学报

ABSTRACT

The emergency and rapid spread of drug resistant parasites and mosquitoes resistant to insecticides urgently demand new tools to control the disease. It is feasible to develop malaria vaccine based on animal and volunteers test. Scientists around the world are working on 3 types of malaria vaccine——pre erythrocytic, blood stage and transmission blocking. Some of the vaccine candidates are being tested in clinical trials and have been shown to be promising. It is very difficult to find a successful malaria vaccine due to its complex life cycle, antigen variations and multiple invasion pathways, but the vaccine will finally be developed.