The Clinical Significance of Cerebrovascular Reserve and Its Determination Methods / 国际脑血管病杂志

ABSTRACT

Cerebrovascular reserve is an important parameter for evaluating cerebrovascular disease,and it has great clinical significance.There are a number of determination methods for cerebrovascular reserve,such as position emission tomography(PET),single photon emission computed tomography(SPECT),Xenon-133 inhalation technique,Xenon CT,perfusion CT, magnetic resonance imaging(MRI),transcranial Doppler(TCD),transcranial harmonic perfusion imaging(HPI),near infrared spectroscopy(NIR),and Laser Doppler vibrometry(LDV), however,there have been no unified criteria up to now.The provocation test that makes cerebral blood flow increase includes CO_2 inhalation test,breath holding test,and acetazolamide test,etc. The article focuses the discussion on the advantages and disadvantages of the above determination methods.