Recent Progress in Research on Small Molecule Agonist of Neurotrophic Factor Receptor Trk / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
;
(12)2006.
Article
in Chinese
| WPRIM
| ID: wpr-679531
ABSTRACT
Neurotrophic factor activates signal pathways of intracellular phosphoinositide 3-kinase and extracellular signal-regulated kinase after acting on Trk receptor tyrosine kinase.It promotes the survival and differentiation of neurons.The development of small molecule Trk agonists of non-peptides and neurotrophic factor simulants can avoid a number of shortcomings of neurotrophic factors while agitating trk receptor signal transduction.It may provide a novel therapeutic approach for the treatment of nervous system diseases.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Cerebrovascular Diseases
Year:
2006
Type:
Article
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