Relation between serum uric acid and metabolic syndrome and coronary artery disease in essential hypertension / 中国实用内科杂志
Chinese Journal of Practical Internal Medicine
; (12)2006.
Article
in Zh
| WPRIM
| ID: wpr-679781
Responsible library:
WPRO
ABSTRACT
Objective To assess the relationship between serum uric acid (SUA)and metabolic syndrome and coronary artery disease(CAD).Methods 232 untreated subjects with essential hypertension were divided into two groups(CAD and no CAD)by coronary angiography.All subjects were free of myocardial infarction,cardiomyopathy,valvular disease, atrial fibrillation,aortic dissection,and renal disease.Results Compared to no CAD group,age,diabetes,triglycerides and SUA in CAD group were higher.There was a significant association between SUA and the severity of CAD (P=0. 015).However,after adjustment for concomitant risk factors of cardiovascular disease,SUA was not an independent risk factor of CAD(P=0.151).In sex-specific analysis,there was a trend of SUA to be an independent risk factor of CAD in women(P=0.062),but it was no statistic significance.The highest quartile level of $UA tended to be associated with increased risk for CAD,but it was not statistically significant either(OR=2.52,P=0.075).SUA was closely associated with metabolic syndrome and diabetes in woman.Conclusion In untreated patients with essential hyperteusion,SUA was associated with metabolic syndrome and the severity of CAD,but it is not an independent risk factor of CAD,the raised SUA may be only a marker of insulin resistance.
Full text:
1
Index:
WPRIM
Type of study:
Risk_factors_studies
Language:
Zh
Journal:
Chinese Journal of Practical Internal Medicine
Year:
2006
Type:
Article