An Intra-procedural Stent Thrombosis in a Prasugrel Resistant Patient Treated with Ticagrelor / 계명의대학술지
Keimyung Medical Journal
;
: 18-24, 2016.
Article
in English
| WPRIM
| ID: wpr-67983
ABSTRACT
Stent thromboses due to multifactorial causes including hypercoagulable conditions and high on treatment platelet reactivity (HTPR), which means a low response to anti-platelet therapy, especially clopidogrel. Prasugrel is a third generation thienopyridine and inactive pro-drug requiring metabolic activation in vivo, which improves the rate of HTPR with clopidogrel. This drug is mostly effective, with a potent, fast, and consistent anti-platelet action, but rare cases of inadequate platelet inhibition with prasugrel have been reported. Here we describe the case of a 47-year-old man who presented with a recurrent acute myocardial infarction and ST during an intravascular ultrasound pullback and was resistant to prasugrel, was successfully treated with ticagrelor.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Thrombosis
/
Blood Platelets
/
Stents
/
Ultrasonography
/
Activation, Metabolic
/
Prasugrel Hydrochloride
/
Myocardial Infarction
Type of study:
Diagnostic study
Limits:
Humans
Language:
English
Journal:
Keimyung Medical Journal
Year:
2016
Type:
Article
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