CT and MRI diagnosis of inflammation and lymphadenosis of lacrimal gland / 眼科

ABSTRACT

Objective To investigate the CT and MRI findings of inflammation and lymphadenosis of lacrimal gland and to assess their diagnostic value.Design Retrospective case series study.Participants 46 patients with inflammation or lymphadenosis of lacrimal gland.Methods CT and MRI findings were analyzed retrospectively in 46 patients with inflammation or lymphadenosis of lacrimal gland,which were confirmed by pathology or clinical follow-ups.Main Outcome Measures Configuration,signal intense(or density)and extent of lesions.Results Of the 46 patients,32 patients with inflammatory pseudotumors demonstrated enlargement of the lacrimal gland,showing homogenous moderate density on CT,isointense or hypointense signal on T_1WI and T_2WI of MRI,and marked contrast enhancement.Multiple cystic components could be seen in one case.In 4 patients with Mikulicz disease,there were bilateral diffuse enlargment of the entire glands.CT scans showed homogenous moderate density.MRI showed hypointense signal on T_1WI and T_2WI,and marked contrast enhancement.Five patients with reactive lymphoid hyperplasia demonstrated enlargement of the lacrimal gland,homogenous moderate density on CT,hypointense or isointense signal on T_1WI and T_2WI(one case was hyperintense signal on T_2WI),and marked contrast enhancement.One patient with atypical lymphoid hyperplasia demonstrated bilateral diffuse enlargment of the entire glands,and homogenous moderate density on CT.4 patients had malignant lymphomas(B-cell lymphoma 3,histocytic sarco- ma 1,all 4 patients had bilateral disease),Those patients with malignant lymphomas showed bilateral diffuse enlargment of the entire glands.Conclusions The CT and MRI findings were similar in inflammation and lymphadenosis of lacrimal gland.CT and MRI may contribute to differentiate inflammation and lymphadenosis with epithelial tumors and may demonstrate the extent of the lesion.(Oph- thalmol CHN,2007,16308-311)